一、研究方向：

1、胰腺恶性肿瘤、神经内分泌肿瘤的临床与基础研究；

2、胆道恶性肿瘤临床与基础研究；

3、肝脏恶性肿瘤临床与基础研究；

至今已主持5项国家自然科学基金、近10项省部级基金资助的课题研究，取得了丰硕的成果。

三、社会兼职：

1、中华医学会外科学分会第十八届委员会胰腺外科学组委员；

2、中国抗癌协会神经内分泌肿瘤专业委员会副主任委员；

3、中国抗癌协会胆道肿瘤专业委员会第四届委员会常委；

4、中国医师协会胰腺病学专业委员会第二届委员会常务委员；

5、中国医师协会外科医师分会机器人外科专家工作组副组长；

6、中国医药教育协会医疗机器人发展促进分会副主任委员；

7、中国研究型医院学会胰腺病学委员会常委；

8、中国研究型医院学会术后快速康复专业委员会常委；

9、中国研究型医院学会智能医学专业委员会常委；

10、国际肝胆胰协会中国分会胆道肿瘤专业委员会副主任委员

11、广东省医学会外科学分会副主任委员

12、广东省医学会肝胆胰外科学分会常务委员；

13、广东省医师协会胰腺病学专业委员会副主任委员；

14、广东省医疗行业协会肝胆胰外科管理分会主任委员；

15、广东省临床医学学会肝胆胰外科专业委员会主任委员；

16、广东省抗癌协会胰腺癌专业委员会副主任委员；

17、广东省抗癌协会胆道肿瘤专业委员会主任委员；

18、Gastroenterology Report》、《中华肝胆外科杂志》、《中华消化外科杂志》、《中华胰腺病学杂志》、《中华普通外科文献杂志》电子版等多家杂志编委。

四、发表论文：

目前已在“Advanced Science (IF=14.3)”、“ACS Nano (IF=15.3)” 、 “Cancer Communications (IF=20.1)”、“Cell Death and Differentiation (IF=13.7)”、“Molecular Therapy (IF=12.1)”、“Cancer Letters (IF=9.1”、“Oncogene (IF=6.9)”、“Int J Biol Sci (IF=8.2)”、“Clin Trans Med (IF=7.9)”、 “Applied Materials Today (IF=7.2)”、“Br J Surg (IF=8.6)”等SCI杂志、及“中华外科杂志”、”中华消化外科杂志”、“中华肝胆外科杂志”、“中国实用外科杂志”等国内核心期刊发表第一作者和（或）通讯作者论文140多篇。近期发表的部分论文如下：

1. Shi YH, Liu ZD, Ma MJ, Zhao GY, Zhu YQ, Wang JQ, Yu YY, Huang XT, Ye JY, Li FX, Wang XY, Xu QC, Yin XY. Platelet-Derived Growth Factor C Facilitates Malignant Behavior of Pancreatic Ductal Adenocarcinoma by Regulating SREBP1 Mediated Lipid Metabolism. Adv Sci (Weinh). 2024 Sep 3:e2407069. doi: 10.1002/advs.202407069. Epub ahead of print. PMID: 39225567. （通讯作者）
2. Zhu YQ, Huang Y, Shi YH, Huang CS, Zhao GY, Liu ZD, Ma MJ, Ye JY, Xu X, Liu Q, Huang XT, Wang JQ, Xu QC, Yin XY. Epigenetic Activation of the CMTM6-IGF2BP1-EP300 Positive Feedback Loop Drives Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma. Adv Sci (Weinh). 2024 Nov 3:e2406714. doi: 10.1002/advs.202406714. Epub ahead of print. PMID: 39488785. （通讯作者）
3. Ma MJ, Shi YH, Liu ZD, Zhu YQ, Zhao GY, Ye JY, Li FX, Huang XT, Wang XY, Wang JQ, Xu QC, Yin XY. N6-methyladenosine modified TGFB2 triggers lipid metabolism reprogramming to confer pancreatic ductal adenocarcinoma gemcitabine resistance. Oncogene. 2024 Jun 24. （通讯作者）
4. Liu ZD, Shi YH, Xu QC, Zhao GY, Zhu YQ, Li FX, Ma MJ, Ye JY, Huang XT, Wang XY, Xu X, Wang JQ, Zhao W, Yin XY. CSNK2A1 confers gemcitabine resistance to pancreatic ductal adenocarcinoma via inducing autophagy. Cancer Lett. 2024 Mar 31;585:216640. doi: 10.1016/j.canlet.2024.216640. Epub 2024 Jan 28. PMID: 38290659. （通讯作者）
5. Huang XT, Qu XF, Zhou JW, Cai JP, Xie JZ, Chen W, Chen LH, Yin XY. Robotic-assisted organ-preserving or parenchymal-sparing pancreatectomy in pancreatic benign or low-grade malignant tumors: a single institute’s experience. J Robotic Surgery. 2024:18:1.（通讯作者）
6. Wang XY, Huang XT, Cai JP, Li B, Chen W, Huang CS, Yin XY. Robotic-Assisted Versus Open Hemi-Hepatectomy: A Propensity Score Analysis. J Surg Res 2024; https://doi.org/10.1016/j.jss.2024.09.001。（通讯作者）
7. Wu X, Li JH, Xu L, Li YX, Zhu XX, Wang XY, Wu X, Zhao W, Ni X, Yin XY. SUMO specific peptidase 3 halts pancreatic ductal adenocarcinoma metastasis via deSUMOylating DKC1. Cell Death Differ. 2023 May 15. doi: 10.1038/s41418-023-01175-4. （通讯作者）
8. Huang XT, Xie JZ, Cai JP, Chen W, Chen LH, Yin XY. Learning curve of robotic-assisted splenic vessel-preserving spleen-preserving distal pancreatectomy by one single surgeon: a retrospective cohort study. BMC Surgery 2023; 23:382. （通讯作者）
9. Huang XT, Cai JP, Yin XY. Robotic-assisted hepatopancreatoduodenectomy and resection of pancreatic tail for one multiple endocrine neoplasia type 1 secreting multiple hormones. HepatoBiliary Surgery and Nutrition 2023; doi: 10.21037/hbsn-23-315. （通讯作者）
10. Huang XT, Wang XY, Xie JZ, Cai JP, Chen W, Chen LH, Yin XY. Learning curves of resection and reconstruction procedures in robotic-assisted pancreatoduodenectomy by a single surgeon: a retrospective cohort study of 160 consecutive cases. Gastroenterol Rep (Oxf). 2023;11:goad042.doi: 10.1093/gastro/goad042.eCollection 2023. （通讯作者）
11. Ye JY, Fang P, Peng ZP, Huang XT, Xie JZ, Yin XY. radiomics-based interpretable model to predict the pathological grade of pancreatic neuroendocrine tumors. European Radiology. 2023; https://doi.org/10.1007/s00330-023-10186-1（通讯作者）
12. Huang XT, Xie JZ, Cai JP, Chen W, Chen LH, Liang LJ, Yin XY. Evaluation of the short-term outcomes of robotic-assisted radical resection for perihilar cholangiocarcinoma: a propensity-scored matching analysis. Gastroenterol Report 2023,11,goad018. （通讯作者）
13. Shi YH, Xu QC, Zhu YQ, Liu ZD, Zhao GY, Liu Q, Wang XY, Wang JQ, Xu X, Su Q, Lai JM, Huang CS, Yin XY. Imatinib facilitates gemcitabine sensitivity by targeting epigenetically activated PDGFC signaling in pancreatic cancer. Mol Ther. 2022 Nov 15:S1525-0016(22)00662-1.（通讯作者）
14. Huang CS, Xu QC, Dai C, Wang L, Tien YC, Li F, Su Q, Huang XT, Wu J, Zhao W, Yin XY. Nanomaterial-Facilitated Cyclin-Dependent Kinase 7 Inhibition Suppresses Gallbladder Cancer Progression via Targeting Transcriptional Addiction. ACS Nano. 2021 Sep 28;15(9):14744-14755. （通讯作者）
15. Xu QC, Tien YC, Shi YH, Chen S, Zhu YQ, Huang XT, Huang CS, Zhao W, Yin XY. METTL3 promotes intrahepatic cholangiocarcinoma progression by regulating IFIT2 expression in an m6A-YTHDF2-dependent manner. Oncogene. 2022 Mar;41(11):1622-1633.（通讯作者） 
16. Huang XT, Li JH, Zhu XX, Huang CS, Gao ZX, Xu QC, Zhao W, Yin XY. HNRNPC impedes m6A-dependent anti-metastatic alternative splicing events in pancreatic ductal adenocarcinoma. Cancer Lett. 2021 Oct 10;518:196-206.（通讯作者）
17. Li YX, Zhu XX, Wu X, Li JH, Ni XH, Li SJ, Zhao W, Yin XY. ACLP promotes activation of cancer-associated fibroblasts and tumor metastasis via ACLP-PPARγ-ACLP feedback loop in pancreatic cancer. Cancer Lett. 2022 Sep 28;544:215802. （通讯作者）
18. Xu QC, Tien YC, Shi YH, Chen SY, Zhu YQ, Huang XT, Huang CS, Zhao W, Yin XY. METTL3 promotes intrahepatic cholangiocarcinoma progression by regulating IFIT2 expression in an m6A-YTHDF2-dependent manner. Oncogene 2022; doi:10.1038/s41388-022-02185-1.（通讯作者）
19.  Huang CS, Zhu YQ, Xu QC, Chen SY, Huang Y, Zhao GY, Ni XH, Liu B, Zhao W, Yin XY. YTHDF2 promotes intrahepatic cholangiocarcinoma progression and desensitizes cisplatin treatment by increasing CDKN1B mRNA degradation Running title YTHDF2 drives ICC progression and chemo-resistance. Clin. Transl. Med. 2022;12:e848.（通讯作者）
20. Li YX, Zhu XX, Wu X, Li JH, Ni XH, Li SJ, Zhao W, Yin XY. ACLP promotes activation of cancer-associated fibroblasts and tumor metastasis via ACLP-PPARγ-ACLP feedback loop in pancreatic cancer. Cancer Letter 2022. https://doi.org/10.1016/j.canlet.2022.215802.（通讯作者）
21.  Ni X; Wu X; Zhu XX; Li JH; Yin XY; Lu L. Carabin Deficiency Aggravates Hepatic Ischemia-Reperfusion Injury Through Promoting Neutrophil Trafficking via Ras and Calcineurin Signaling. Front Immunol.2022;13;773291.（共同通讯作者）
22. Huang CS, Xu QC, Dai CL, Wang LY, Tien YC, Li FX, Su Q, Huang XT, Wu J, Zhao W, Yin XY. Nanomaterial-Facilitated Cyclin-Dependent Kinase7 Inhibition Suppresses Gallbladder Cancer Progression via Targeting Transcriptional Addiction. ACS Nano. 2021;15(9):14744-14755. （通讯作者）
23. Huang XT, Cai JP, Chen W, Huang CS, Li JH. Gang TT, Liang LJ, Yin XY. Establishment and validation of a nomogram for predicting overall survival of node negative perihilar cholangiocarcinoma. Asian J Surg. 2022;45:712-717. （通讯作者）
24. Cai JP, Chen W, Chen LH, Wang XY, Lai JM, Yin XY. Comparison between robotic-assisted and laparoscopic left hemi-hepatectomy. Asian J Surg 2022;45(1):265-268. （通讯作者）
25. Huang XT, Li JH, Zhu XX, Huang CS, Gao ZX, Xu QC, Zhao W, Yin XY. HNRNPC impedes m6 A-dependent anti-metastatic alternative splicing events in pancreatic ductal adenocarcinoma. Cancer Letter. 2021;518:196–206. （通讯作者）
26. Xu QC, Wang LY, Tong T, Huang XT, Huang CS, Li FX, Su Q, Tien YC, Wu J, Zhao W, Yin XY. Efficient Delivery of BRD4 Inhibitor by Glutathione-sensitive Nanoparticle to Suppress Gallbladder Cancer Through Inhibiting NF-κB Signaling. Applied Material Today 2020;21:100849. （通讯作者）
27. Wang XY, Cai JP, Song LL, Huang CS, Chen W, Huang XT, Chen SF, Liu XY, Yin XY. Identification of Genomic Alterations in Sporadic Pancreatic Neurogenic Tumors. Pancreas 2020;49:1393-1397. （通讯作者）
28. Huang XT, Huang CS, Liu C, Chen W, Cai JP, Cheng H, Jiang XX, Liang LJ, Yu XJ, Yin XY. Development and Validation of a New Nomogram for Predicting Clinically Relevant Postoperative Pancreatic Fistula After Pancreatoduodenectomy. World J Surg 2021, 45, 261-269. （通讯作者）
29. Huang XT, Huang CS, Li JH, Chen W, Gan TT, Wang XY, Liang LJ, Yin XY. Evaluating the adequacy of nodal status in node-negative gallbladder cancer with T1b-T2 stages: use of nodal staging score. HPB (Oxford) 2021;23(5):795-801.（通讯作者）
30. Huang CS, You X, Dai C, Xu QC, Li F, Wang L, Huang XT, Wang JQ, Li SJ, Gao Z, Wu J, Yin XY, Zhao W. Targeting Super-Enhancers via Nanoparticle-Facilitated BRD4 and CDK7 Inhibitors Synergistically Suppresses Pancreatic Ductal Adenocarcinoma. Adv. Sci. 2020, 7(7):1902926.（共同通讯作者）
31. Chen HD, Huang CS, Xu QC, Li FX, Huang XT, Wang JQ, Li SJ, Zhao W, Yin XY. Therapeutic Targeting of CDK7 Suppresses Tumor Progression in Intrahepatic Cholangiocarcinoma. Int J Biol Sci. 2020;16(7):1207-1217.（通讯作者）
32. Wang JQ, Wang LY, Li SJ, Tong T, Wang L, Huang CS, Xu QC, Huang XT, Li JH, Wu J, Zhao W, Yin XY. Histone methyltransferase G9a inhibitor-loaded redox-responsive nanoparticles for pancreatic ductal adenocarcinoma therapy. Nanoscale. 2020;12(29):15767-15774.（通讯作者）
33. Huang XT, Huang CS, Li JH, Xu QC, Yin XY. Use of nodal staging score in evaluating the accuracy of pathologic nodal status in node-negative ampullary carcinoma. J Gastrointestinal Surg. 2021;25:1001-1009.（通讯作者）
34. Zhu XX, Li JH, Cai JP, Hou X, Huang CS, Huang XT, Wang JQ, Li SJ, Xu QC, Yin XY. EYA4 inhibits hepatocellular carcinoma by repressing MYCBP by dephosphorylating β-catenin at Ser552. Cancer Sci. 2019;110(10):3110-3121.（通讯作者）
35. Huang XT, Huang CS, Chen W, Cai JP, Gan TT, Zhao Y, Liu Q, Liang LJ, Yin XY. Development and validation of a nomogram for predicting overall survival of node-negative ampullary carcinoma. J Surg Oncol. 2020;121(1):518–523.（通讯作者）
36. Gao SW, Huang CS, Huang XT, Chen LH, Chen W, Cai JP, Yin XY. Ki-67 Index of 5% is Better Than 2% in Stratifying G1 and G2 of WHO Grading System in Pancreatic Neuroendocrine Tumors. Pancreas 2019; 48(6):795-798. （通讯作者）
37. Huang XT, Chen LH, Huang CS, Li JH, Cai JP, Chen W, Yin XY. Establishment of a Nomogram by Integrating Molecular Markers and Tumor-Node-Metastasis Staging System for Predicting the Prognosis of Hepatocellular Carcinoma. Dig Surg. 2019;36(5):426-432.（通讯作者）
38. 黄锡泰 谢锦钊 蔡建鹏 许琼聪 黄晨松 陈流华 陈伟 殷晓煜。单一术者机器人辅助胰十二指肠切除术的近期疗效分析。中华消化外科杂志，2024；23（4）:596-600.
39. 殷晓煜。胆囊管癌的临床特征及治疗。中国实用外科杂志。2023；43（11）:56-58.
40. 殷晓煜.机器人辅助肝门部胆管癌根治术的应用现状、优势及局限性.中华腔镜外科杂志（电子版）.2022;15(2):69-72.
41. 蔡建鹏，陈伟，王曦域，陈流华，殷晓煜。机器人辅助胰十二指肠切除术在高龄患者的应用。中华腔镜外科杂志。2021；14（1）：10-14. （通讯作者）
42. 陈流华，黄锡泰，陈伟，赖佳明，梁力建，殷晓煜。全尾状叶切除在肝门部胆管癌根治术中的应用。中华肝脏外科手术学杂志。2021；10（6）：559-563。（通讯作者）
43. 黄锡泰、蔡建鹏、陈伟、房鹏，陈流华，殷晓煜。机器人辅助保留脾脏远端胰腺切除术围手术期指标回顾性研究。中国实用外科杂志。2021；41（12）:1407-1422. （通讯作者）
44. 黄晨松，钟记华，陈伟，蔡建鹏，赖佳明，梁力建，殷晓煜。不同类型胰腺囊性肿瘤的诊断与治疗。中华消化外科杂志。2020；19（12）：1-7. （通讯作者）

五、专著：

1. Yin XY. Diagnosis. In: Lau WY (ed). Hilar cholangiocarcinoma. Springer Science Business Media Dordrecht & People’s Medical Publishing House. 2013:91-98.