医疗特长:
擅长鼻部炎症性疾病及鼻颅底肿瘤的鼻内镜微创手术治疗。尤其在鼻窦炎、鼻息肉、鼻腔鼻窦良恶性肿瘤、儿童鼾症、腺样体、扁桃体肥大及成人鼾症的内镜微创手术治疗积累了丰富经验。对慢性鼻窦炎伴哮喘,难治性鼻窦炎的药物和手术治疗有深入的研究。对过敏性鼻炎的药物治疗、免疫治疗、生物治疗和手术治疗有深入研究。
研究方向:上气道炎症性疾病,包括慢性鼻窦炎和鼻息肉,尤其是难治性慢性鼻窦炎,伴哮喘的慢性鼻窦炎,变应性鼻炎。
主要教育和工作经历:
- 2001年9月-2008年7月 中山大学临床医学七年制专业
硕士阶段(2006年9月-2008年7月)在中山大学附属第一医院耳鼻喉科学习,师从我国著名鼻科专史剑波教授学习,研究方向为鼻科学,研究课题为《慢性鼻-鼻窦炎合并哮喘患者的临床特征和功能性鼻内镜鼻窦手术疗效分析》,2008年获硕士学位;
- 2012年9月-2015年7月 中山大学附属第一医院耳鼻喉科 博士阶段
继续跟随史剑波教授学习,研究方向为鼻科学,研究课题为《伴有气道高反应的慢性鼻-鼻窦炎的诊疗优化研究》,2015年获得博士学位;
- 2017年1月-2019年6月,美国德州大学西南医学中心(University of Texas, Southwestern Medical Center)免疫系从事博士后研究,合作导师为David J Farrar. 研究方向为变态反应,课题为《The suppression effect of type Ⅰinterferon on CD4+ memory cells in allergic rhinitis》
社会兼职:
中国人体健康科技促进会耳鼻喉科分会委员
广东省药学会耳鼻咽喉头颈外科用药专委员会委员
广东省医师协会变态反应工作委员会青年医师专业组组员
论著:
- Li C, Zhang B, Yan M, Li Y, Chen J, Nie Z, Guo Y, Shi J, Chen F. Cluster Analysis of Patients with Chronic Rhinosinusitis and Asthma after Endoscopic Sinus Surgery. Ann Allergy Asthma Immunol. 2022 Nov 24:S1081-1206(22)01955-X. doi: 10.1016/j.anai.2022.11.013.
- Nie Z, Xu Z, Fan Y, Guo Y, Chen C, Liu W, Li Y, Lai Y, Shi J, Chen F.
Clinical characteristics of central compartment atopic disease in Southern China.Int Forum Allergy Rhinol. 2022 Jul 28. doi: 10.1002/alr.23069.
- Chen F, Rowe RK, Gill MA, Farrar JD. Type I interferon suppresses memory Th2 cell cytokine secretion from allergic subjects. Allergy. 2020 Mar;75(3):695-698. doi: 10.1111/all.14056. Epub 2019 Oct 8.
- Cao Y, Chen F, Sun Y, Hong H, Wen Y, Lai Y, Xu Z, Luo X, Chen Y, Shi J, Li H.LL-37 promotes neutrophil extracellular trap formation in chronic rhinosinusitis with nasal polyps. Clin Exp Allergy. 2019 Jul;49(7):990-999. doi: 10.1111/cea.13408. Epub 2019 May 29.(共一)
- Cao Y, Hong H, Sun Y, Lai Y, Xu R, Shi J, Chen F. The effects of endoscopic sinus surgery on pulmonary function in chronic rhinosinusitis patients with asthma: a systematic review and meta-analysis. Eur Arch Otorhinolaryngol. 2019 May;276(5):1405-1411. doi: 10.1007/s00405-019-05337-4. Epub 2019 Feb 25.(通讯)
- 曹玉洁 徐睿 陶逍遥 史剑波 陈枫虹. 基于百度指数分析中国变应性鼻炎流行的时空特征. 中华耳鼻咽喉头颈外科杂志2019 年12月第54 卷第12期(通讯)
- Hong H, Chen F, Sun Y, Yang Q, Gao W, Cao Y, Fan Y, Shi J, Li H. Nasal IL25 predicts the response to oral-corticosteroid in chronic rhinosinusitis with nasal polyps (CRSwNP). J Allergy Clin Immunol. 2018 May;141(5):1890-1892. doi: 10.1016/j.jaci.2017.10.050. Epub 2018 Jan 11.(共一)
- Hong H, Chen F, Zheng X, Liao W, Liao Z, Cao Y, He H, Zhu Z, Fan Y. Decreased frequency of adenoidectomy by a 12-week nasal budesonide treatment. Ther Clin Risk Manag. 2017 Oct 3;13:1309-1316. doi: 10.2147/TCRM.S144659. eCollection 2017. (共一) 2.2,1178-203X
- Chen F, Hong H, Sun Y, Hu X, Zhang J, Xu G, Zhao W, Li H, Shi J. Nasal interleukin 25 as a novel biomarker for patients with chronic rhinosinusitis with nasal polyps and airway hypersensitiveness: A pilot study. Ann Allergy Asthma Immunol. 2017 Sep 1. pii: S1081-1206(17)30553-7. doi: 10.1016/j.anai.2017.07.012.
- Hong H, Chen F, Sun Y, Hu X, Wei Y, Fan Y, Zhang J, Wang D, Xu R, Li H, Shi J. Local IL-25 contributes to Th2-biased inflammatory profiles in nasal polyps. Allergy. 2017 Aug 3. DOI: 10.1111/all.13267. (共一)
- Hong H, Chen F, Qiao Y, Yan Y, Zhang R, Zhu Z, et al. GSK-3beta activation index is a potential indicator for recurrent inflammation of chronic rhinosinusitis without nasal polyps. J Cell Mol Med. 2017 Jul 17. doi: 10.1111/jcmm.13274. (共一)
- Zheng R, Chen FH, Gao WX, Wang D, Yang QT, Wang K, et al. The TH2-polarizing function of atopic interleukin 17 receptor B-positive dendritic cells up-regulated by lipopolysaccharide. Ann Allergy Asthma Immunol 2017;118(4):474-482 e471. (共一)
- Liu J, Chen FH, Qiu SQ, Yang LT, Zhang HP, Liu JQ, et al. Probiotics enhance the effect of allergy immunotherapy on regulating antigen specific B cell activity in asthma patients. Am J Transl Res 2016;8(12):5256-5270. (共一)
- Chen FH, Deng J, Hong HY, Xu R, Guo JB, Hou WJ, et al. Extensive versus functional endoscopic sinus surgery for chronic rhinosinusitis with nasal polyps and asthma: A 1-year study. Am J Rhinol Allergy 2016;30(2):143-148.
- Chen F, Luo X, Xu R, Deng J, Zuo K, Li H, Shi J. Evaluation of airway hyperresponsiveness in chronic rhinosinusitis: values of sinus computed tomography. Ann Allergy Asthma Immunol 2014; 113(6): 609-613.
- Chen FH, Zuo KJ, Feng SY, Guo JB, Fan YP, Shi JB, Li HB. A modified surgical procedure for endoscopic optic nerve decompression for the treatment of traumatic optic neuropathy. N Am J Med Sci. 2014 Jun; (6):270-3. doi: 10.4103/1947-2714.134372.
- Xu R, Chen FH, Zuo KJ, Ye,XL, Yang QT, Shi JB, Chen HX, Li HB. Endoscopic optic nerve decompression for patients with traumatic optic neuropathy: is nerve sheath incision necessary? ORL J Otorhinolaryngol Relat Spec. 2014;76(1):44-9. doi: 10.1159/000358305. (并列第一)
- Zuo KJ, Guo JB, Chen FH, Xu R, Xu G, Li HB. Clinical characteristics and surrogate markers of eosinophilic chronic rhinosinusitis in Southern China. Eur Arch Otorhinolaryngol. 2014 Sep; 271(9):2461-8. doi: 10.1007/s00405-014-2910-0.
- Chen FH, Zuo KJ, Guo YB, Li ZP, Xu G, Xu R, Shi JB. Long-term results of endoscopic sinus surgery-oriented treatment for chronic rhinosinusitis with asthma. Laryngoscope. 124(1): 24-8,2014.
- Luo Q, Chen F, Liu W, et al. Evaluation of Long-Term Clarithromycin Treatment in Adult Chinese Patients with Chronic Rhinosinusitis without Nasal polyps. ORL J Otorhinolaryngol Relat Spec. 73(4):206-11, 2011.
- Liu W, Li Z, Luo Q, Lai Y, Zhang J, Chen F, Shi J, Li H, Xiong G, Xu G, Wang H. The elevated expression of osteopontin and vascular endothelial growth factor in sinonasal inverted papilloma and its relationship with clinical severity. Am J Rhinol Allergy. 25(5):313-7, 2011.
- Chen FH, Rui X, Deng J,et al. Endoscopic sandwich technique for moderate nasal septal perforations. Laryngoscope. 122(11):2367-72, 2012.
- Shi JB, Chen FH, Fu QL, et al. Frontal sinus cerebrospinal fluid leaks: repair in 15 patients using an endoscopic surgical approach. ORL J Otorhinolaryngol Relat Spec. 2010;72(1):56-62. (共同第一)
- Shi J, Luo Q, Chen F, et al. Induction of IL-6 and IL-8 by house dust mite allergen Der p1 in cultured human nasal epithelial cells is associated with PAR/PI3K/NFkappaB signaling. ORL J Otorhinolaryngol Relat Spec. 2010;72(5):256-65.
- 陈枫虹,徐睿,左可军等. 慢性鼻-鼻窦炎合并哮喘患者的功能性鼻内镜鼻窦手术疗效分析. 中华耳鼻咽喉头颈外科杂志.46(6):444-448,2011.
- 史剑波,陈枫虹,徐睿等. 鼻内镜鼻窦手术眼部并发症及其处理对策.中华耳鼻咽喉头颈外科杂志.2008:43(2):114-119.
- 史剑波,陈枫虹,徐睿等. 经鼻内镜扩大鼻丘进路额窦手术的探索. 中华耳鼻咽喉头颈外科杂志.2011:46(6):459-462.
- 陈枫虹,王章锋,文卫平等.功能性鼻内镜鼻窦手术治疗老年慢性鼻-鼻窦炎鼻息肉的安全性评估.老年医学与保健2010:16(5):283-285,296.
- 陈枫虹,史剑波,许庚等.后筛骨瘤致视力下降一例. 中华耳鼻咽喉头颈外科杂志.2008:43(8):622-623.
- 欧洲鼻-鼻窦炎鼻息肉诊疗意见书2007摘录. 史剑波,陈枫虹,文卫平等译.中华耳鼻咽喉头颈外科杂志.2008:43(4):317-320.
- 2010年欧洲鼻腔鼻窦颅底肿瘤内镜诊疗意见书摘译.史剑波,孙悦奇,陈枫虹等译. 中华耳鼻咽喉头颈外科杂志.2011:46(2):172-176.
其他主要工作成绩(比如获奖情况):
2021年广东省科技进步奖一等奖
2021年第二届中华医学会中青年鼻内镜手术视频大赛南部赛区第一名
2019年第7届中国医师协会耳鼻喉年会鼻科病例比赛第一名
2015年全国鼻科手术病例分享赛总决赛冠军
2015年全国鼻科年会大会发言优秀论文一等奖