研究方向:
长期从事腹壁功能、腹腔肿瘤与免疫调控相关的基础与临床研究,重点探究补体免疫系统对胃肠功能的调控机理。围绕疝、感染免疫、营养和消化肿瘤共发表1作或通讯作者SCI论文50余篇,总引用次数1200余次。主持国自然基金1项,参与多项国自然基金。目前工作重心为各型疝病与胃肠肿瘤的微创手术治疗(腹腔镜辅助手术、快速康复外科等)和临床研究。
主要教育和工作经历:
· 南京大学医学院附属金陵医院 普通外科研究所 研究生(2008~2012)
· 中山大学附属第一医院 胃肠胰外科 住院医(2012~2014)
· 中山大学附属第一医院 胃肠外科中心 主治医师 (2015~2021)
· 中山大学附属第一医院 胃肠外科中心 副主任医师(2022~至今)
社会兼职:
· 广东省消化外科分会&疝外科分会委员
· 欧洲疝学会(EHS)会员
· 美国外科医师协会(ACS)助理院士
· 学术杂志审稿专家(Expert Reviewer)和客座编辑(Invited Editor),涉及杂志包括“International Immunopharmacology,Annals of Surgical Oncology,Cancer Management and Research,Journal of Cancer Research and Therapeutics,OncoTargets and Therapy,Journal of Oncology,Cancer Biology & Medicine,Journal of Surgical Oncology,BMC Cancer,消化肿瘤杂志(电子版)”等
· 互联网医疗平台胃肠与疝病科普专家
论著:
· Fatty acid oxidation controls CD8+ tissue-resident memory T cell survival in gastric adenocarcinoma. Cancer Immunology Research, 2020.
· Complement C3 overexpression activates JAK2/STAT3 pathway and correlates with gastric cancer progression. Journal Experimental Clinical Cancer Research, 2020, 39: 9.
· Effect of CRP and Kinetics of CRP in Prognosis of Nasopharyngeal Carcinoma. Frontiers in Oncology, 2019, 9: 89.
· Deperitoneum biological mesh repair for abdominal wall hernia: a novel wound healing promotion idea. Minim Invasive Ther Allied Technol, 2019, 28: 143-150.
· Does Lymphadenectomy with at Least 15 Perigastric Lymph Nodes Retrieval Promise an Improved Survival for Gastric Cancer: A Retrospective Cohort Study in Southern China. Journal of Cancer, 2019, 10: 1444-1452.
· Postoperative pain investigation under the protocol of enhanced recovery after abdominal surgery: incidence and risk factors. International Journal of Clinical and Experimental Medicine, 2019.
· Risk factors of postoperative complications after emergency repair of incarcerated groin hernia for adult patients: a retrospective cohort study. Hernia, 2019, 23: 267-276.
· The mTORC1 signaling modulated by intracellular C3 activation in Paneth cells promotes intestinal epithelial regeneration during acute injury. International Immunopharmacology, 2019, 67: 54-61.
· Intracellular activation of complement C3 in Paneth cells improves repair of intestinal epithelia during acute injury. Immunotherapy, 2018, 10: 1325-1336.
· External validation of a modified 8th AJCC TNM system for advanced gastric cancer: Long-term results in Southern China. Surgical Oncology 2018, 27: 146-153.
· Crosstalk between prognostic long noncoding RNAs and messenger RNAs as transcriptional hallmarks in gastric cancer. Epigenomics, 2018, 10: 433-443.
· Deperitoneum Biological Mesh Repair for Abdominal Wall Hernia: a Novel Wound Healing Promotion Idea. Minimally Invasive Therapy & Allied Technologies 2018, 2018: 1-8.
· Exploration of the optimal treatment regimens for Esthesioneuroblastoma: a single center experience in China. Journal of Cancer 2018, 9(1):174-181.
· 应用猪小肠黏膜下层脱细胞基质补片行腹壁切口疝修补术19例疗效观察. 中国实用外科杂志 2018:08.
· 杂交技术切口疝修补术中应用生物补片的效果观察——单中心5年随访结果分析. 中华胃肠外科杂志 2018:07.
· 第8版日本《大肠癌诊疗规范》解读. 消化肿瘤杂志(电子版) 2018:03.
专著:
· 《普通外科围术期管理及并发症处理经典病例解析》(人民卫生出版社,2016年,章节参编)
其他主要工作成绩(比如获奖情况):
· 香港外科学临床年会最佳大会发言奖 Hongkong Best Award 2018年
· 中国解放军全军科技进步一等奖(7/10) 2014年